Latest Research

The central vein sign and paramagnetic rim lesions can clarify complex diagnoses and lessen reliance on lumbar punctures, thereby reducing costs.

Multiple sclerosis clinicians in Australia report that guideline application can improve standards of care but report varying practices in applying treatment guidelines.

Serum neurofilament light chain measurement can help identify individuals with radiologically isolated syndrome who are at high risk for multiple sclerosis conversion.

Walking while directing attention to other cognitively demanding tasks can negatively impact gait stability in people with multiple sclerosis.

This paper describes participant outreach and recruitment strategies for an ongoing, remotely delivered, culturally tailored exercise training program for African American individuals with multiple sclerosis.

Walking while directing attention to other cognitively demanding tasks can negatively impact gait stability in people with multiple sclerosis.

Occupational therapists treating people with multiple sclerosis reporting sexual function challenges should consider a counseling intervention using the Permission, Limited Information, Specific Suggestions, and Intensive Therapy model or the Good Enough Sex model to improve self-reported sexual function.

Nearly 25% of people with multiple sclerosis in our study reported wearing off prior to their next ocrelizumab infusion while on the standard 6-month dosing interval.

Head rotation (HR) negatively affects balance and walking performance in people with multiple sclerosis (MS). Specifically, during walking, individuals with MS lose their walking rhythm for a few steps after HR, which represents a significant performance decline and may partly explain their increased risk of falling.

Despite worsening physical outcomes, people with multiple sclerosis 55 years and older experience stable or improving mental health.

As the population with multiple sclerosis ages, clinicians are increasingly caring for older adults living with the disease.

This editorial maps RiMS’s activities and aligns it with the WHO’s 10 priority areas, assessing its contributions and identifying gaps to enhance the understanding of RiMS’ role in contributing to these priorities and to inform the adaptation of strategic action plans to ensure alignment with global priorities.

People with multiple sclerosis face unique uncertainties during and around pregnancy, including uncertainty about the future, the symptoms they experience, and information availability.

Assessments and interventions to improve sleep quality and manage dysfunctional sleep beliefs in people with MS may improve health-related quality of life and functioning. Cognitive behavioral therapy for insomnia targets both factors and has been demonstrated to be a modifiable and efficacious treatment in this population.

There is insufficient bone health risk assessment, screening, and management; there is also an absence of health care and lifestyle self-management information about the risk and prevention of poor bone health for people with multiple sclerosis.

This study aimed to use a combination of qualitative and quantitative methods to compare physician and computer-based identification of new/enlarging brain T2 lesions obtained during a clinical trial.

The use of cooling vests may limit the effects of thermosensitivity in people with multiple sclerosis, as evidenced by improved 6-minute walk test performance compared with an uncooled condition.

Individuals with multiple sclerosis (MS) have a higher rate of migraine than the general population. Both conditions are associated with psychiatric comorbidity and cognitive symptoms that should be monitored given the potential for additive burden when MS and migraine co-occur.

Sexual and gender minority individuals with multiple sclerosis face additional challenges, including stigma, discrimination, and health care disparities, which can limit access to sexual health services, including family planning and gender-affirming care.

Acute aerobic exercise using various modalities resulted in temporary worsening of sensory function, with increased pain and physical exhaustion for up to 24 hours for people with advanced multiple sclerosis.

People with multiple sclerosis report that even minor word-finding difficulties, which may manifest as substitutions or prolonged pauses for search, can impact their ability to engage in everyday communication.

Electronic administration of mental health and fatigue screeners before multiple sclerosis appointments improves the detection of related concerns.

Disaster events disproportionally affect persons with disabilities; as there is an increasing likelihood of disasters globally, clinicians should consider identifying resources to prepare patients for disasters.

For a clinical audience, our team’s efforts highlight that usual care looks different across clinics, regions, and countries, which highlights the importance of interpreting the results of trials with usual care comparators carefully.

People with multiple sclerosis (MS) are underinformed about pregnancy and MS, with gaps in knowledge regarding their ability to have children, risk of relapse during pregnancy and the postpartum period, and treatment options.

Although more common in younger patients, tumefactive demyelination can occur in adults 65 years and older. It should be considered as a differential diagnosis in patients of this age presenting with a central nervous system lesion.