The central vein sign and paramagnetic rim lesions can clarify complex diagnoses and lessen reliance on lumbar punctures, thereby reducing costs.
The aim of this article is to report a unique case of familial multiple sclerosis from Saudi Arabia with 2 novel variants in the HLA-DRB1 gene that may contribute to the pathogenesis.
Serum neurofilament light chain measurement can help identify individuals with radiologically isolated syndrome who are at high risk for multiple sclerosis conversion.