Optic Neuritis Revisited

Optic neuritis (ON) refers to a retrobulbar inflammatory process of the optic nerve and frequently manifests as the first clinical symptom of multiple sclerosis (MS). The diagnosis is established on clinical grounds and is complemented by magnetic resonance imaging, which provides prognostic information about the future risk of MS. The results of large-scale clinical trials have enhanced understanding of the relationship between ON and MS.